Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929669 | 0.71 | ALOX15 (0.45) | KDM4E | |
| SCHEMBL1048319 | 0.70 | PPARG (0.47) | KDM4E | |
| SCHEMBL1049954 | 0.69 | HEXA (0.34) | — | |
| SCHEMBL3968786 | 0.69 | NOTUM (0.42) | KDM4E | |
| SCHEMBL3292160 | 0.67 | IKBKB (0.43) | KDM4E | |
| SCHEMBL3291369 | 0.67 | NOTUM (0.43) | KDM4E | |
| SCHEMBL1045445 | 0.67 | NOTUM (0.43) | KDM4E | |
| SCHEMBL1929990 | 0.66 | CYP1A2 (0.46) | KDM4E | |
| SCHEMBL1930103 | 0.65 | MAPT (0.50) | KDM4E | |
| SCHEMBL1928637 | 0.65 | S1PR1 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148246-B2 | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20040198786-A1 | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198786-A1 | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals | GPR119, CPT1A, PC | TRPV3 3935/4885KDM4E 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.