Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275551 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL10584292 | 0.82 | CYP3A4 (0.48) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL9963710 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL18848621 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL16770733 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL27363114 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL10333201 | 0.79 | TSHR (0.54) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL3786798 | 0.79 | CYP3A4 (0.54) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL14645078 | 0.78 | USP2 (0.46) | ALDH1A1HPGDALOX15HSD17B10GAA | |
| SCHEMBL11514222 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067668-B2 | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-0990648-B1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA (JP) | 2005-11-02 | — | — | EP | disclosed |
| CN-1169794-C | 4-quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | �����Ƹ���ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6680282-B2 | FUNGICIDE HAVING AN EXCELLENT CONTROL EFFECT; 4-QUINOLINOL DERIVATIVES HAVING SPECIFIC SUBSTITUENT AT 1,2 AND ATLEAST ONE SUBSTITUENT AT 5,6,7,8 POSITION | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| CN-1259124-A | 4-quinolyl phenol derivatives and agricultural and horticultural fungicides containing the same as the active ingredient | RHONE POULENC YUKA AGRO KABUSH (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-0990648-A1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | Meiji Seika Kaisha, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | CYP51A1, CYP4X1, CYP4Z1 | ALDH1A1 229/4885HPGD 3338/4885ALOX15 3949/4885 |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | CYP51A1, DDT, PGLS | ALDH1A1 741/4885HPGD 2467/4885ALOX15 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.