Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076562 | 0.94 | KMT2A (0.75) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6075693 | 0.80 | KMT2A (1.00) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6076593 | 0.79 | HPGD (1.00) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL5248141 | 0.78 | HPGD (0.74) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL5248148 | 0.78 | HPGD (0.74) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL4532306 | 0.78 | MAN1B1 (0.57) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL13438260 | 0.77 | USP2 (0.93) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL1709325 | 0.77 | HPGD (0.72) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL4091917 | 0.77 | HPGD (0.72) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL28741579 | 0.77 | HPGD (0.72) | KMT2AMEN1HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |