Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6075693 | 0.99 | KMT2A (1.00) | HPGDKMT2AMEN1USP2POLB | |
| SCHEMBL6076562 | 0.85 | KMT2A (0.75) | HPGDKMT2AMEN1USP2POLB | |
| SCHEMBL6076695 | 0.79 | KMT2A (0.66) | HPGDKMT2AMEN1USP2POLB | |
| SCHEMBL13438260 | 0.78 | USP2 (0.93) | HPGDKMT2AMEN1USP2POLB | |
| SCHEMBL20179555 | 0.78 | HPGD (0.62) | HPGDKMT2AMEN1POLBTSHR | |
| SCHEMBL5567016 | 0.77 | HPGD (1.00) | HPGDKMT2AMEN1POLBTSHR | |
| SCHEMBL4070763 | 0.77 | NPC1 (0.73) | HPGDKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6077387 | 0.76 | HPGD (0.62) | HPGDKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6077865 | 0.76 | HPGD (0.97) | HPGDKMT2AMEN1POLBTSHR | |
| SCHEMBL8269659 | 0.75 | USP2 (0.76) | HPGDKMT2AMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |