Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076695 | 0.94 | KMT2A (0.66) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6075693 | 0.86 | KMT2A (1.00) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6076593 | 0.85 | HPGD (1.00) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL6077865 | 0.79 | HPGD (0.97) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL5567016 | 0.78 | HPGD (1.00) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL5248141 | 0.76 | HPGD (0.74) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL5248148 | 0.76 | HPGD (0.74) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL15680134 | 0.76 | RAB9A (0.82) | KMT2AHPGDALDH1A1POLBRAB9A | |
| SCHEMBL15330996 | 0.76 | KMT2A (0.55) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL13118269 | 0.75 | RAB9A (0.97) | KMT2AMEN1HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |