Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077778 | 0.71 | KMT2A (0.37) | LMNAADORA3MAPTALDH1A1KMT2A | |
| SCHEMBL15669931 | 0.69 | MAPT (0.48) | LMNAADORA3MAPTALDH1A1KMT2A | |
| SCHEMBL1894049 | 0.69 | MAPT (0.48) | LMNAADORA3MAPTALDH1A1KMT2A | |
| SCHEMBL1895535 | 0.69 | MAPT (0.48) | LMNAADORA3MAPTALDH1A1KMT2A | |
| SCHEMBL6078148 | 0.68 | NPSR1 (0.43) | LMNAKMT2AKDM4EGAAMEN1 | |
| SCHEMBL11400689 | 0.66 | KMT2A (0.40) | LMNACYP3A4MAPTALDH1A1KMT2A | |
| SCHEMBL6078380 | 0.66 | TACR1 (0.47) | CYP3A4CYP2C9CYP2C19MAPTKDM4E | |
| Methane SCHEMBL11336749 | 0.65 | MAPT (0.48) | LMNAADORA3MAPTALDH1A1KMT2A | |
| SCHEMBL6077284 | 0.65 | KMT2A (0.40) | MAPTALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9525052 | 0.65 | DDB1 (0.44) | MAPTALDH1A1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | claimed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | claimed |
| EP-1471067-A1 | Derivatives of 2-oxothiadiazoline-4-carboxylic acid and its use as active photoprotective agent | L'OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | disclosed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | disclosed |
| EP-1471067-A1 | Derivatives of 2-oxothiadiazoline-4-carboxylic acid and its use as active photoprotective agent | L'OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | CUTA, OGDH, TYR | LMNA 3284/4885ADORA3 2460/4885AR 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.