Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19478537 | 0.87 | ALDH1A1 (0.59) | ALDH1A1GAAHSD17B10USP2PKM | |
| SCHEMBL5132140 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GAAHSD17B10HPGDCYP3A4 | |
| SCHEMBL84557 | 0.82 | ALDH1A1 (0.57) | ALDH1A1GAAHSD17B10CYP3A4TDP1 | |
| SCHEMBL11466249 | 0.82 | ALDH1A1 (0.57) | ALDH1A1GAAHSD17B10CYP3A4TDP1 | |
| SCHEMBL8298141 | 0.82 | ALDH1A1 (0.60) | ALDH1A1GAAHSD17B10USP2PKM | |
| SCHEMBL22477433 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAAHSD17B10CYP3A4TDP1 | |
| SCHEMBL1597428 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAAHSD17B10CYP3A4TDP1 | |
| SCHEMBL13523902 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAHSD17B10HPGDCYP3A4 | |
| SCHEMBL12909064 | 0.79 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10USP2PKM | |
| SCHEMBL9782923 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10USP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067668-B2 | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-0990648-B1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA (JP) | 2005-11-02 | — | — | EP | disclosed |
| CN-1169794-C | 4-quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | �����Ƹ���ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6680282-B2 | FUNGICIDE HAVING AN EXCELLENT CONTROL EFFECT; 4-QUINOLINOL DERIVATIVES HAVING SPECIFIC SUBSTITUENT AT 1,2 AND ATLEAST ONE SUBSTITUENT AT 5,6,7,8 POSITION | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| CN-1259124-A | 4-quinolyl phenol derivatives and agricultural and horticultural fungicides containing the same as the active ingredient | RHONE POULENC YUKA AGRO KABUSH (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-0990648-A1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | Meiji Seika Kaisha, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | CYP51A1, CYP4X1, CYP4Z1 | ALDH1A1 229/4885GAA 426/4885HSD17B10 141/4885 |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | CYP51A1, DDT, PGLS | ALDH1A1 741/4885GAA 344/4885HSD17B10 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.