⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610675 | 0.97 | ALDH1A1 (0.41) | — | |
| SCHEMBL609091 | 0.97 | — | — | |
| SCHEMBL22762181 | 0.97 | ALDH1A1 (0.41) | — | |
| SCHEMBL11055329 | 0.93 | — | — | |
| Acetic Acid SCHEMBL30330000 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL7863270 | 0.86 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL30330016 | 0.79 | MLYCD (0.31) | — | |
| SCHEMBL18944380 | 0.79 | HTT (0.47) | — | |
| SCHEMBL16977024 | 0.77 | CA2 (0.45) | — | |
| SCHEMBL25045002 | 0.75 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586476-B1 | METHOD OF PRODUCING REPRODUCIBLE PARTICLES | MEDINVENT SA (SE) | 1996-03-27 | — | — | EP | claimed |
| EP-4223754-A1 | COMPOUND AS AKT KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-09 | — | — | EP | disclosed |
| CN-110248949-B | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2022261243-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| US-11052092-B2 | N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating autoimmune diseases | GENFIT (FR) | 2021-07-06 | — | — | US | disclosed |
| EP-3377060-B1 | PYRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-08-19 | — | — | EP | disclosed |
| EP-3239183-B1 | MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER | SUMITOMO CHEMICAL CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2019-08-22 | — | — | US | disclosed |
| US-10118973-B2 | Modified conjugated diene polymer, and polymer composition containing said polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-11-06 | — | — | US | disclosed |
| WO-2009100095-A1 | 3-(4-FLUOROPHENYL)-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC ACTIVITY | ALLERGAN, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20080095806-A1 | Composition And Method For Treating Inflammatory Diseases Using Protease Inhibitors | PROMETIC BIOSCIENCES, INC. (CA) | 2008-04-24 | — | — | US | disclosed |
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |
| US-7208139-B2 | Conducting nuclear spin tomography on a patient who has been administered a cascade polymer complex having complex-forming ligands for imaging of inflammation and/or tumors in the brain | SCHERING AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-20070066674-A1 | Tricyclic imidzopyridines for use as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2007-03-22 | — | — | US | disclosed |
| WO-2005117955-A1 | TREATMENT OF ATOPIC DERMATITIS WITH UNGLYCOSYLATED ALPHA ONE-ANTITRYPSIN | ARRIVA PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1562621-A1 | COMPOSITION AND METHOD FOR TREATING INFLAMMATORY DISEASES USING PROTEASE INHIBITORS | Arriva-Prometic Inc. (CA) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004045634-A1 | COMPOSITION AND METHOD FOR TREATING INFLAMMATORY DISEASES USING PROTEASE INHIBITORS | ARRIVA-PROMETIC INC. (CA) | 2004-06-03 | — | — | WO | disclosed |
| US-4956107-A | OIL ADDITIVE COMPRISING POLYOLEFIN MODIFIES BY AN UNSATURATED MONOCARBOXYLIC ACID AND THE REACTION PRODUCT OF A POLYAMINE AND ESTER, THIOESTER, AMIDE OR THIOAMIDE | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4238609-A | Production of ampho-ionic compounds | NIPPON PAINT CO., LTD. (JP) | 1980-12-09 | — | — | US | disclosed |