Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076056 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL6077207 | 0.82 | LMNA (0.53) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL6076622 | 0.80 | LMNA (0.70) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL14142610 | 0.78 | LMNA (0.80) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL6077347 | 0.78 | LMNA (0.55) | ALDH1A1LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6077138 | 0.78 | LMNA (0.65) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL14493689 | 0.77 | EPHX1 (0.61) | ALDH1A1TSHRMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL6078444 | 0.74 | LMNA (0.60) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL23012627 | 0.74 | LMNA (0.56) | ALDH1A1TSHRLMNAMAPTRAB9A | |
| SCHEMBL27322979 | 0.74 | LMNA (0.68) | ALDH1A1TSHRLMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |