Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079348 | 0.89 | MEN1 (0.51) | ALDH1A1GAAL3MBTL1MAPTMEN1 | |
| SCHEMBL6078676 | 0.83 | LMNA (0.64) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6078277 | 0.82 | LMNA (0.67) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6079643 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6079143 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6429403 | 0.79 | LMNA (0.62) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6079065 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6078043 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6078993 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL6078213 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-6458998-B1 | NAPHTHALENEUREAS AS ANTIDIABETIC AGENTS | TELIK, INC. | 2002-10-01 | — | — | US | disclosed |