Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120006 | 0.86 | CES2 (0.53) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL14609300 | 0.84 | ALDH1A1 (0.53) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL31633615 | 0.83 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL1228223 | 0.83 | CES2 (0.64) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL8153445 | 0.83 | ALDH1A1 (0.47) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL9221780 | 0.80 | CES2 (0.55) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL29120007 | 0.80 | L3MBTL1 (0.50) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL9203015 | 0.80 | ALDH1A1 (0.49) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL27757257 | 0.79 | NPC1 (0.51) | CES2CES1L3MBTL1LMNANAPRT | |
| SCHEMBL29554609 | 0.79 | L3MBTL1 (0.55) | CES2CES1L3MBTL1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506149-A | Prolyl hydroxylase inhibitors and methods of use | PROCTER & GAMBLE (US) | 2009-08-12 | — | — | CN | claimed |
| CN-101506149-A | Prolyl hydroxylase inhibitors and methods of use | PROCTER & GAMBLE (US) | 2009-08-12 | — | — | CN | disclosed |
| US-7115612-B2 | Arylsulfonamides as antiviral agents | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-03 | — | — | US | disclosed |
| US-20040176374-A1 | Arylsulfonamides as antiviral agents | AIC246 AG & CO. KG (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176374-A1 | Arylsulfonamides as antiviral agents | IFNAR1, ARSA, TPMT | CES2 223/4885CES1 149/4885L3MBTL1 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.