Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078568 | 0.94 | MEN1 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6079442 | 0.93 | MEN1 (0.50) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6078719 | 0.93 | MEN1 (0.55) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6079082 | 0.91 | LMNA (0.48) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6079055 | 0.87 | PRMT1 (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6078658 | 0.86 | MEN1 (0.57) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6079588 | 0.85 | LMNA (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6079074 | 0.84 | LMNA (0.54) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6079368 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6079497 | 0.82 | MEN1 (0.55) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-6458998-B1 | NAPHTHALENEUREAS AS ANTIDIABETIC AGENTS | TELIK, INC. | 2002-10-01 | — | — | US | disclosed |