SCHEMBL607903

SCHEMBL607903

CC(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.66
ALB P02768 1/20 0.54
IL2 P60568 1/20 0.54
LMNA P02545 1/20 0.53
TACR1 P25103 1/20 0.51
CA1 P00915 5/20 0.50
FOLH1 Q04609 4/20 0.50
MME P08473 1/20 0.47
ACE P12821 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
FPR2 P25090 1/20 0.47
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
EGFR P00533 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ALOX15 P16050 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL604816 1.00 CA2 (0.66) CA2ALBIL2LMNATACR1
SCHEMBL328475 0.87 MME (0.60) CA2LMNACA1FOLH1MME
SCHEMBL468823 0.87 MME (0.60) CA2LMNACA1FOLH1MME
SCHEMBL9787629 0.87 MME (0.60) CA2LMNACA1FOLH1MME
SCHEMBL29367167 0.87 MME (0.60) CA2LMNACA1FOLH1MME
SCHEMBL3981526 0.85 CA2 (0.62) CA2ALBIL2CA1FOLH1
SCHEMBL27086746 0.85 CA2 (0.61) CA2ALBIL2CA1FOLH1
SCHEMBL27086749 0.85 CA2 (0.61) CA2ALBIL2CA1FOLH1
SCHEMBL4799488 0.84 LMNA (0.52) CA2LMNATACR1CA1FOLH1
SCHEMBL27477803 0.84 LMNA (0.52) CA2ALBIL2LMNATACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1540341-A4 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIV ROCHESTER MEDICAL CT (US) 2007-01-10 EP claimed
US-20060166295-A1 Method for determination of likelihood of occurrence of preterm labor in pregnant females NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-07-27 US claimed
EP-1540341-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES The University of Rochester Medical Center (US) 2005-06-15 EP claimed
WO-2004003555-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) 2004-01-08 WO claimed
EP-2299275-B1 Classification of the oncofetal fibronection level for pregnancy-related indications ADEZA BIOMEDICAL CORP (US) 2018-03-07 EP disclosed
US-9513298-B2 Methods for detecting oncofetal fibronectin BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2016-12-06 US disclosed
US-20150044708-A1 Methods for Detecting Oncofetal Fibronectin HOLOGIC, INC. 2015-02-12 US disclosed
US-8852872-B2 Methods for detecting oncofetal fibronectin HOLOGIC, INC. (US) 2014-10-07 US disclosed
US-20130171672-A1 Methods for Detecting Oncofetal Fibronectin HOLOGIC, INC. (US) 2013-07-04 US disclosed
US-8372581-B2 Methods for detecting oncofetal fibronectin CYTYC CORPORATION (US) 2013-02-12 US disclosed
US-20120040356-A1 Methods for Detecting Oncofetal Fibronectin CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP 2012-02-16 US disclosed
US-7943294-B2 Methods for detecting oncofetal fibronectin HOLOGIC, INC. (US) 2011-05-17 US disclosed
US-20060024724-A1 Oncofetal fibronectin as a marker for health and disease CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP 2006-02-02 US disclosed
US-6939716-B2 Method for detecting conditions indicative of sepsis WASHINGTON UNIVERSITY (US) 2005-09-06 US disclosed
EP-1540341-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES The University of Rochester Medical Center (US) 2005-06-15 EP disclosed
EP-1427845-A2 METHOD FOR DETECTING SEPSIS Washington University (US) 2004-06-16 EP disclosed
WO-2004003555-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) 2004-01-08 WO disclosed
US-20030100122-A1 Method for detecting conditions indicative of sepsis WASHINGTON UNIVERSITY 2003-05-29 US disclosed
WO-2003025212-A2 METHOD FOR DETECTING SEPSIS WASHINGTON UNIVERSITY (US) 2003-03-27 WO disclosed
US-4745124-A THIO/ESTER PEPTIDES UNIVERSITY OF MIAMI (US) 1988-05-17 US disclosed