Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078109 | 0.96 | PLAU (0.72) | PLAUALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6427777 | 0.92 | PLAU (0.66) | PLAUALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6078913 | 0.91 | KDM4E (0.67) | PLAUALDH1A1GAASMN1; SMN2ALOX15 | |
| SCHEMBL7663909 | 0.89 | PLAU (0.66) | PLAUALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL6429753 | 0.89 | PLAU (0.60) | PLAUALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6078100 | 0.88 | TCF4 (0.68) | PLAUALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6428098 | 0.86 | PLAU (0.59) | PLAUALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6079658 | 0.85 | GAA (0.62) | ALDH1A1MAPTGAASMN1; SMN2LMNA | |
| SCHEMBL6078536 | 0.84 | PRMT1 (0.60) | PLAUALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6078558 | 0.84 | TCF4 (0.65) | PLAUMAPTSMN1; SMN2LMNAPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |