Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789916 | 0.88 | KMT2A (0.75) | CASP6MEN1KMT2AALDH1A1PKM | |
| SCHEMBL6078420 | 0.87 | PLAU (0.50) | CASP6MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL6077882 | 0.86 | ALDH1A1 (0.77) | CASP6MEN1KMT2AALDH1A1 | |
| SCHEMBL6078356 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL6078762 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1PKMAKR1C3 | |
| SCHEMBL6079248 | 0.85 | MEN1 (0.58) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6077873 | 0.85 | TSHR (0.59) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6078851 | 0.84 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6427650 | 0.82 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL6079433 | 0.82 | ALDH1A1 (0.71) | CASP6MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |