Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKLR | P30613 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079494 | 0.88 | CASP6 (0.59) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7322058 | 0.85 | MEN1 (0.75) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL9996812 | 0.83 | ALDH1A1 (0.81) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7789908 | 0.83 | HIF1A (0.62) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7782154 | 0.80 | ALDH1A1 (0.77) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7789864 | 0.79 | MEN1 (0.52) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7789865 | 0.79 | MEN1 (0.52) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL9997222 | 0.79 | MCL1 (0.62) | KMT2AMEN1ALDH1A1PKMCASP6 | |
| SCHEMBL7790018 | 0.78 | CAPN1 (0.53) | KMT2AMEN1ALDH1A1AKR1C3PKM | |
| SCHEMBL7790014 | 0.78 | CAPN1 (0.53) | KMT2AMEN1ALDH1A1AKR1C3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |