SCHEMBL6079779

SCHEMBL6079779

Cc1c(C(=O)O)nc2c(O)cccc2c1N1CCN(C)CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HRH4 Q9H3N8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6079499 0.89 ALDH1A1 (0.41) KDM4AMEN1KMT2A
SCHEMBL6080144 0.87 KDM4E (0.43) KDM4AMEN1KMT2A
SCHEMBL6080164 0.80 HRH4 (0.46) HRH4
SCHEMBL6080384 0.76 KDM4E (0.46) KDM4AMEN1KMT2A
SCHEMBL6080015 0.76 ALDH1A1 (0.40) MEN1KMT2A
SCHEMBL6591671 0.74 KDM4A (0.48) KDM4AMEN1KMT2A
SCHEMBL6080749 0.73 CYP1A2 (0.54) KDM4AKMT2A
Hydrochloric Acid SCHEMBL6079508 0.73 KDM4A (0.47) KDM4AMEN1KMT2A
SCHEMBL6080761 0.72 MAPT (0.47) MEN1KMT2A
SCHEMBL27472343 0.70 NCF1 (0.47) MEN1KMT2AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060183909-A1 Compositions derived from quinoline and quinoxaline, preparation and use thereof NEURO3D (FR) 2006-08-17 US claimed
US-20060183909-A1 Compositions derived from quinoline and quinoxaline, preparation and use thereof NEURO3D (FR) 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183909-A1 Compositions derived from quinoline and quinoxaline, preparation and use thereof NQO1, NQO2, RECQL KDM4A 849/4885MEN1 740/4885KMT2A 1384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.