Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081248 | 0.88 | THRA (0.41) | PTGER1THRATHRBALDH1A1KDM4E | |
| SCHEMBL6080313 | 0.86 | TSHR (0.41) | PTGER1ALDH1A1KDM4EPTPN1MAPT | |
| SCHEMBL6080030 | 0.85 | PTGER1 (0.41) | PTGER1THRATHRBALDH1A1KDM4E | |
| SCHEMBL6080654 | 0.84 | LTB4R (0.41) | PTGER1ALDH1A1KDM4EPTPN1MAPT | |
| SCHEMBL6081092 | 0.81 | LTB4R (0.41) | PTGER1ALDH1A1KDM4EPTPN1EDNRA | |
| SCHEMBL6079317 | 0.81 | LTB4R (0.39) | PTGER1ALDH1A1KDM4EPTPN1MAPT | |
| SCHEMBL6079768 | 0.81 | ALDH1A1 (0.38) | PTGER1ALDH1A1KDM4EPTPN1MAPT | |
| SCHEMBL6080359 | 0.79 | BACE1 (0.47) | — | |
| SCHEMBL6080121 | 0.79 | PTPN1 (0.41) | PTGER1THRATHRBALDH1A1KDM4E | |
| SCHEMBL6080186 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTTDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | PTGER1 1819/4885THRA 4854/4885THRB 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.