Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080865 | 0.89 | CYP4A11 (0.43) | CYP4A11NQO2CYP4F2TNKS2LCK | |
| SCHEMBL6080727 | 0.85 | IGFBP5 (0.36) | TNKS2KDM4EMAPTALOX15TSHR | |
| SCHEMBL6080238 | 0.85 | PLA2G2A (0.42) | NQO2ALDH1A1KDM4EMAPTPKM | |
| SCHEMBL6080853 | 0.85 | NQO2 (0.35) | NQO2ALDH1A1GAAGFERLCK | |
| SCHEMBL6080014 | 0.82 | CA1 (0.38) | NQO2GAA | |
| SCHEMBL6080283 | 0.80 | EGFR (0.42) | NQO2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL6080256 | 0.79 | NQO2 (0.45) | NQO2ALDH1A1GAALCKKDM4E | |
| SCHEMBL6079518 | 0.79 | NQO2 (0.45) | NQO2ALDH1A1GAAGFERLCK | |
| SCHEMBL6081104 | 0.78 | NQO2 (0.45) | NQO2ALDH1A1GAAGFERLCK | |
| SCHEMBL21044485 | 0.77 | CYP4A11 (0.56) | CYP4A11NQO2CYP4F2TNKS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | CYP4A11 539/4885NQO2 2/4885CYP4F2 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.