Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044363 | 0.89 | CYP4A11 (0.51) | CYP4A11CYP4F2MAPK1CYP1A2GAA | |
| SCHEMBL21044489 | 0.85 | MAPT (0.40) | CYP4A11CYP4F2DAGLAMAPK1CYP1A2 | |
| SCHEMBL20886389 | 0.82 | MAPK1 (0.41) | MAPK1CYP1A2GAAMAPTRECQL | |
| SCHEMBL17911801 | 0.82 | MAPK1 (0.43) | CYP4A11CYP4F2MAPK1CYP1A2GAA | |
| SCHEMBL4871286 | 0.81 | CYP4A11 (0.54) | CYP4A11CYP4F2MAPK1KDM4EALDH1A1 | |
| SCHEMBL6080865 | 0.80 | CYP4A11 (0.43) | CYP4A11CYP4F2TNKS2DAGLACES1 | |
| SCHEMBL20886358 | 0.80 | GABRP (0.46) | MAPK1CYP1A2GAAMAPTRECQL | |
| SCHEMBL6079952 | 0.77 | CYP4A11 (0.41) | CYP4A11CYP4F2TNKS2GAAMAPT | |
| SCHEMBL26162767 | 0.77 | MTNR1A (0.38) | MAPK1CYP1A2GAAMAPTRECQL | |
| SCHEMBL21044526 | 0.77 | CYP4F2 (0.44) | CYP4A11CYP4F2MAPK1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |