Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228055 | 0.95 | AR (0.49) | ARKDM4EMAPTCA12CA9 | |
| SCHEMBL13849655 | 0.80 | CA12 (0.48) | ARKDM4ECA12CA9CA1 | |
| SCHEMBL13849654 | 0.80 | GRIN2D (0.53) | ARCA12CA9CA1CA3 | |
| SCHEMBL13849659 | 0.78 | CA12 (0.47) | ARKDM4ECA12CA9CA1 | |
| SCHEMBL9703662 | 0.75 | AR (0.52) | ARKDM4EMAPTCA12CA9 | |
| SCHEMBL718661 | 0.73 | CA12 (0.46) | ARCA12CA9CA1CA3 | |
| SCHEMBL11552058 | 0.71 | ATM (0.58) | ARKDM4EMAPTCA12CA9 | |
| SCHEMBL1437934 | 0.71 | ALDH1A1 (0.49) | ARKDM4EMAPTCA12CA9 | |
| SCHEMBL17951770 | 0.69 | MAPK1 (0.68) | ARMAPTCA12CA9CA1 | |
| SCHEMBL31497397 | 0.69 | CA12 (0.44) | ARKDM4EMAPTCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859599-B2 | Androgen receptor modulating compounds, preparation and uses thereof | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-10-14 | — | — | US | disclosed |
| US-8741951-B2 | Non-steroidal compounds for androgen receptor modulation | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-06-03 | — | — | US | disclosed |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | NR5A1, AR, SHBG | AR 2/4885KDM4E 2249/4885MAPT 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.