Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186961 | 0.89 | DRD2 (0.43) | CA1CA2KDM4EGPR84AHR | |
| SCHEMBL24086184 | 0.77 | GPR84 (0.48) | CA1CA2KDM4EGPR84AHR | |
| SCHEMBL5912311 | 0.75 | CYP2D6 (0.40) | GPR84AHRCMA1TYRCSNK2A1 | |
| SCHEMBL1437934 | 0.74 | ALDH1A1 (0.49) | CA12CA1CA2CA9KDM4E | |
| Indole SCHEMBL1932756 | 0.73 | CA1 (0.55) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL608013 | 0.69 | AR (0.53) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL15290389 | 0.69 | MAPT (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL9703662 | 0.68 | AR (0.52) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL6308105 | 0.68 | MAPT (0.52) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL20916098 | 0.68 | CA12 (0.43) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490487-A | Polysubstituted tetrahydrocarbazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-02-21 | — | — | CN | disclosed |