Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080347 | 0.90 | MRGPRX4 (0.42) | ALDH1A1MRGPRX4MAPTKDM4EADORA3 | |
| SCHEMBL6596767 | 0.88 | MRGPRX4 (0.47) | MRGPRX4MAPTADORA3ADORA2AADORA1 | |
| SCHEMBL6079903 | 0.86 | ALDH1A1 (0.44) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL6080646 | 0.84 | NOTUM (0.42) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL31389266 | 0.83 | ALOX15 (0.55) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL6081085 | 0.82 | NOTUM (0.41) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL6079313 | 0.82 | NOTUM (0.41) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL6079765 | 0.82 | NOTUM (0.41) | ALDH1A1USP2TSHRHSD17B10NOTUM | |
| SCHEMBL6079273 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10LMNAHPGD | |
| SCHEMBL6079823 | 0.81 | LMNA (0.50) | ALDH1A1USP2TSHRHSD17B10NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | ALDH1A1 2726/4885USP2 3376/4885TSHR 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.