Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747227 | 0.90 | LMNA (0.49) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL13652292 | 0.81 | LMNA (0.47) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL31384368 | 0.81 | LMNA (0.43) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL439635 | 0.81 | APP (0.48) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL3247140 | 0.81 | KDM4E (0.48) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL3828983 | 0.80 | KDM4E (0.42) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL11070962 | 0.78 | KDM4E (0.44) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL16589027 | 0.78 | ALK (0.44) | LMNAKDM4EALDH1A1HPGDGLA | |
| SCHEMBL11712521 | 0.77 | LMNA (0.54) | LMNAKDM4EMAPK1NPSR1ALDH1A1 | |
| SCHEMBL6148137 | 0.77 | LMNA (0.65) | LMNAKDM4EMAPK1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | NQO2, NRDC, IFNG | LMNA 2488/4885KDM4E 4544/4885MAPK1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.