Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437945 | 0.87 | ACHE (0.47) | APPACHEHTR1AADRA1DADRA1A | |
| SCHEMBL439021 | 0.84 | KMT2A (0.55) | KDM4EMAP4K4LMNAMAPTMAPK1 | |
| SCHEMBL31384368 | 0.81 | LMNA (0.43) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL440060 | 0.81 | BCHE (0.50) | APPBCHEACHECHRM1GRIN1 | |
| SCHEMBL2949117 | 0.81 | KDM4E (0.46) | APPBCHEACHECHRM1KDM4E | |
| SCHEMBL13652181 | 0.81 | KDM4E (0.49) | APPBCHEACHECHRM1GRIN1 | |
| SCHEMBL29393432 | 0.81 | KDM4E (0.46) | APPBCHEACHECHRM1KDM4E | |
| SCHEMBL6080573 | 0.81 | LMNA (0.47) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL440348 | 0.80 | NPC1 (0.44) | APPACHEKDM4ELMNAABCC8 | |
| SCHEMBL442244 | 0.78 | ACHE (0.43) | BCHEACHEGRIN1GRIN2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |