Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 9/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645986 | 0.85 | ABCB1 (0.66) | ABCB1ABCC1KCNMA1HCAR3NPC1 | |
| SCHEMBL17457465 | 0.82 | ABCB1 (0.69) | ABCB1ABCC1KCNMA1HCAR3NPC1 | |
| SCHEMBL17457463 | 0.82 | ABCB1 (0.69) | ABCB1ABCC1KCNMA1HCAR3NPC1 | |
| SCHEMBL6081078 | 0.82 | KDM4E (0.51) | ABCB1ABCC1HCAR3NPC1MAPK1 | |
| SCHEMBL6080571 | 0.82 | APP (0.59) | KCNMA1HCAR3NPC1MAPK1RAB9A | |
| SCHEMBL22439814 | 0.80 | ABCB1 (0.68) | ABCB1ABCC1KCNMA1NPC1MAPK1 | |
| SCHEMBL7981545 | 0.79 | HCAR3 (0.58) | ABCB1ABCC1KCNMA1HCAR3HTT | |
| SCHEMBL6080678 | 0.78 | PKM (0.59) | NPC1MAPK1RAB9AALDH1A1HTT | |
| SCHEMBL2282371 | 0.77 | MAPT (0.68) | ABCB1ABCC1KCNMA1NPC1RAB9A | |
| SCHEMBL6587509 | 0.77 | ABCC1 (0.59) | ABCB1ABCC1KCNMA1HCAR3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | ABCB1 405/4885ABCC1 346/4885KCNMA1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.