Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081119 | 0.83 | RNASEH1 (0.44) | DHODHNQO2GPR35IGFBP3RNASEH1 | |
| SCHEMBL6080184 | 0.81 | MEN1 (0.38) | EPRS1GPR35KDM4EMAPTTDP1 | |
| SCHEMBL6080976 | 0.79 | MEN1 (0.36) | RNASEH1KDM4AKDM4ERAB9AKMT2A | |
| SCHEMBL6079954 | 0.78 | PIN1 (0.39) | DHODHRNASEH1MAPTCYP1A2CYP2C19 | |
| SCHEMBL6080445 | 0.76 | MAPT (0.47) | MAPTTDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6079819 | 0.76 | DHODH (0.36) | DHODHIGFBP3KDM4AKDM4EMAPT | |
| SCHEMBL6080337 | 0.73 | CDK9 (0.41) | DHODHKDM4EMAPTCDK9DYRK1A | |
| SCHEMBL6080384 | 0.72 | KDM4E (0.46) | KDM4AKDM4EMAPTRAB9AKMT2A | |
| SCHEMBL6080475 | 0.70 | KDM4E (0.44) | NQO2GPR35IGFBP3KDM4AKDM4E | |
| SCHEMBL6080544 | 0.70 | KDM4E (0.34) | DHODHKDM4EMAPTRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | EPRS1 3165/4885DHODH 188/4885NQO2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.