Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079920 | 0.87 | HPGDS (0.47) | KMT2AKDM4EL3MBTL1MAPK1HPGDS | |
| SCHEMBL6080248 | 0.80 | HPGDS (0.47) | KMT2AKDM4EL3MBTL1HPGDSPDE3B | |
| SCHEMBL6079724 | 0.78 | CYP1A2 (0.47) | KMT2AKDM4EL3MBTL1HPGDSPDE3B | |
| SCHEMBL7781701 | 0.76 | NQO2 (0.53) | KMT2AKDM4EHPGDSPDE3BPDE3A | |
| SCHEMBL1883218 | 0.75 | HPGDS (0.48) | KMT2AKDM4EL3MBTL1HPGDSPDE3B | |
| SCHEMBL8905796 | 0.75 | TDP1 (0.47) | KMT2AKDM4EL3MBTL1MAPK1MAPT | |
| SCHEMBL6567173 | 0.75 | LMNA (0.49) | KMT2AKDM4EL3MBTL1MAPK1HPGDS | |
| SCHEMBL4701058 | 0.74 | KDM4E (0.56) | KMT2AKDM4EL3MBTL1HPGDSPDE3B | |
| SCHEMBL9650028 | 0.73 | NQO2 (0.47) | KMT2AKDM4EHPGDSPDE3BPDE3A | |
| SCHEMBL2200731 | 0.73 | HPGDS (0.75) | KMT2AKDM4EL3MBTL1MAPK1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KMT2A 1384/4885KDM4E 1006/4885L3MBTL1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.