Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611088 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR | |
| SCHEMBL9147481 | 0.76 | TDP1 (0.38) | ALDH1A1CYP2A6MAPTHPGD | |
| SCHEMBL24398866 | 0.74 | ATM (0.39) | ALDH1A1CYP2A6LMNASMN1; SMN2KDM4E | |
| SCHEMBL710758 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR | |
| SCHEMBL19903270 | 0.74 | MAOA (0.39) | ALDH1A1CYP2A6HSD17B10LMNAHPGD | |
| SCHEMBL611208 | 0.73 | HPGD (0.46) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL18602990 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10LMNAMAPTHPGD | |
| SCHEMBL8595279 | 0.71 | ALDH1A1 (0.54) | ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR | |
| SCHEMBL20323528 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL195687 | 0.70 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3372589-B1 | PYRIMIDINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2021-10-20 | — | — | EP | disclosed |
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150099823-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
| EP-2857446-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-8334339-B2 | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20120041134-A1 | CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |