Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595279 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALDH3A1ALDH1A3CYP2A6MAOA | |
| SCHEMBL346860 | 0.80 | SLC6A4 (0.56) | ALDH1A1GSK3BSLC6A4MAOANPC1 | |
| SCHEMBL3405047 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1ALDH1A3CYP2A6MAOA | |
| SCHEMBL5198346 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GSK3BSLC6A4MAOATDP1 | |
| SCHEMBL2622606 | 0.77 | GSK3B (0.46) | GSK3BSLC6A4MAOANPC1RAB9A | |
| SCHEMBL18885132 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1ALDH1A3CYP2A6HPGD | |
| SCHEMBL10424504 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1ALDH1A3CYP2A6HPGD | |
| SCHEMBL7323727 | 0.77 | GSK3B (0.46) | ALDH1A1GSK3BSLC6A4MAOANPC1 | |
| SCHEMBL20319851 | 0.77 | GSK3B (0.46) | ALDH1A1GSK3BSLC6A4MAOANPC1 | |
| SCHEMBL10656224 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1ALDH1A3CYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298630-A | Reacting 2-alkylthiobenzaldehyde derivative with halo compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-03-29 | — | — | US | claimed |
| EP-0572712-A2 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-12-08 | — | — | EP | claimed |
| JP-1100155-A | — | — | None | — | — | JP | disclosed |
| US-20240300934-A1 | COMPOUNDS FOR MODULATING MYCOBACTERIUM TUBERCULOSIS RESPONSE | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2024-09-12 | — | — | US | disclosed |
| WO-2023283608-A1 | COMPOUNDS FOR MODULATING MYCOBACTERIUM TUBERCULOSIS RESPONSE | TRUSTEES OF TUFTS COLLEGE (US) | 2023-01-12 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-2814814-B1 | IMIDAZOLYLKETONE DERIVATIVES ASD ALDOSTERONE SYNTHASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018042342-A1 | 1,2,3-BENZOTRIAZOLE DERIVATIVES AS ROR GAMMA T MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-03-08 | — | — | WO | disclosed |
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |
| US-9464058-B2 | Imidazolylketone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| JP-H01100155-A | CINNAMOYLALKANE DERIVATIVE COMPOUND | NIPPON OIL & FATS CO LTD | 1989-04-18 | — | — | JP | disclosed |
| US-4517192-A | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics | STERLING DRUG INC. (US) | 1985-05-14 | — | — | US | disclosed |
| US-4396553-A | Tetrahydronaphthalene and indane compounds useful as anti-tumor agents | HOFFMANN-LA ROCHE INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-3946028-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946027-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3943140-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | HAVCR2, HDLBP, HSP90B1 | ALDH1A1 3831/4885GSK3B 942/4885ALDH3A1 4000/4885 |
| US-20240300934-A1 | COMPOUNDS FOR MODULATING MYCOBACTERIUM TUBERCULOSIS RESPONSE | IFNG, NFATC1, RELA | ALDH1A1 1559/4885GSK3B 2225/4885ALDH3A1 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.