Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695890 | 0.89 | HPGD (0.50) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL29497287 | 0.83 | HPGD (0.43) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL9737132 | 0.83 | HPGD (0.43) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL10495789 | 0.83 | HSD17B10 (0.52) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL4736891 | 0.82 | HPGD (0.55) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL31621320 | 0.81 | MAPK1 (0.48) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL10946030 | 0.81 | MAPK1 (0.48) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL31621319 | 0.81 | MAPK1 (0.48) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL21574928 | 0.78 | TRPV4 (0.41) | MAPK1HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL28599115 | 0.78 | ALDH1A1 (0.44) | MAPK1HPGDALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018537-B2 | Chiral stationary phases based on derivatives of 4-amino-3,5-dinitrobenzoic acid | CHIRALLICA D.O.O. (HR) | 2006-03-28 | — | — | US | claimed |
| US-20040144708-A1 | Chiral stationary phases based on derivatives of 4-amino-3,5-dinitrobenzoic acid | EURAND PHARMACEUTICALS LTD. (IE) | 2004-07-29 | — | — | US | claimed |
| EP-1370356-A1 | CHIRAL STATIONARY PHASES BASED ON DERIVATIVES OF 4-AMINO-3,5-DINITROBENZOIC ACID | EURAND PHARMACEUTICALS LTD. (IE) | 2003-12-17 | — | — | EP | claimed |
| WO-2002070124-A1 | CHIRAL STATIONARY PHASES BASED ON DERIVATIVES OF 4-AMINO-3,5-DINITROBENZOIC ACID | EURAND PHARMACEUTICALS LTD (IE) | 2002-09-12 | — | — | WO | claimed |
| EP-2255653-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2255649-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2255644-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| US-7018537-B2 | Chiral stationary phases based on derivatives of 4-amino-3,5-dinitrobenzoic acid | CHIRALLICA D.O.O. (HR) | 2006-03-28 | — | — | US | disclosed |
| US-20040144708-A1 | Chiral stationary phases based on derivatives of 4-amino-3,5-dinitrobenzoic acid | EURAND PHARMACEUTICALS LTD. (IE) | 2004-07-29 | — | — | US | disclosed |
| EP-1370356-A1 | CHIRAL STATIONARY PHASES BASED ON DERIVATIVES OF 4-AMINO-3,5-DINITROBENZOIC ACID | EURAND PHARMACEUTICALS LTD. (IE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002070124-A1 | CHIRAL STATIONARY PHASES BASED ON DERIVATIVES OF 4-AMINO-3,5-DINITROBENZOIC ACID | EURAND PHARMACEUTICALS LTD (IE) | 2002-09-12 | — | — | WO | disclosed |