Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497287 | 1.00 | HPGD (0.43) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL4736891 | 0.89 | HPGD (0.55) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL3695890 | 0.84 | HPGD (0.50) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL6082482 | 0.83 | MAPK1 (0.55) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL9417291 | 0.78 | CYP3A4 (0.39) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL6082210 | 0.75 | MAPK1 (0.46) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL22839898 | 0.75 | MAPT (0.38) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL21574928 | 0.74 | TRPV4 (0.41) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL10495789 | 0.73 | HSD17B10 (0.52) | HPGDCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL9790158 | 0.73 | ALDH1A1 (0.44) | HPGDCYP3A4ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153350-A | Process for preparing 3,4,6-trifluorophithalonitrile | PFIZER INC., A CORPORATION OF DE | 1992-10-06 | — | — | US | claimed |
| US-5153350-A | Process for preparing 3,4,6-trifluorophithalonitrile | PFIZER INC., A CORPORATION OF DE | 1992-10-06 | — | — | US | disclosed |
| US-5153350-A | Process for preparing 3,4,6-trifluorophithalonitrile | PFIZER INC., A CORPORATION OF DE | 1992-10-06 | — | — | US | disclosed |
| US-4239686-A | Process for producing phthalimido derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-12-16 | — | — | US | disclosed |