Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902716 | 0.98 | MAPT (0.36) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| SCHEMBL570499 | 0.98 | MAPT (0.36) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL8827832 | 0.96 | MAPT (0.39) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL5450059 | 0.96 | MAPT (0.39) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| Iodide SCHEMBL5144330 | 0.84 | MAPT (0.38) | MAPTSLC22A16CYP1A2MEN1LMNA | |
| SCHEMBL8055941 | 0.82 | MAPT (0.39) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| SCHEMBL1057053 | 0.82 | MAPT (0.39) | MAPTSLC22A16CYP1A2MAPK1MEN1 | |
| Iodide SCHEMBL400576 | 0.75 | MAPT (0.40) | MAPTSLC22A16CYP1A2MEN1LMNA | |
| SCHEMBL6153646 | 0.73 | MAPT (0.41) | MAPTSLC22A16CYP1A2MEN1LMNA | |
| SCHEMBL77665 | 0.73 | MAPT (0.41) | MAPTSLC22A16CYP1A2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060839-A | Vegetable pesticide residue rapid screening and detecting method | 云浮市云安区农业发展服务中心 | 2026-05-19 | — | — | CN | claimed |
| CN-119372283-B | Cholinesterase determination reagent and application thereof | 中生北控生物科技股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119372283-A | Cholinesterase determination reagent and application thereof | 中生北控生物科技股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-115722210-B | Recursive nanofiber-based detection material and preparation method and application thereof | 广西大学 | 2024-02-20 | — | — | CN | claimed |
| CN-106680222-B | Cholinesterase measures reagent and kit | 郑州科欣生物技术有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-106680222-A | Reagent for determining cholinesterase and kit | 郑州科欣生物技术有限公司 | 2017-05-17 | — | — | CN | claimed |
| EP-2035032-A2 | METHODS FOR ESTER DETOXICATION | Human Biomolecular Research Institute (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2007146003-A2 | METHODS FOR ESTER DETOXICATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2007-12-21 | — | — | WO | claimed |
| US-20070286846-A1 | Novel methods for ester detoxication | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2007-12-13 | — | — | US | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| EP-0533283-B1 | Assay for serum cholinesterase acitivity | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-12-11 | — | — | EP | claimed |
| US-5272061-A | Assay for serum cholinesterase activity | EASTMAN KODAK COMPANY (US) | 1993-12-21 | — | — | US | claimed |
| EP-0533283-A1 | Assay for serum cholinesterase acitivity | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-03-24 | — | — | EP | claimed |
| CN-122060839-A | Vegetable pesticide residue rapid screening and detecting method | 云浮市云安区农业发展服务中心 | 2026-05-19 | — | — | CN | disclosed |
| EP-4153561-B1 | 9H-FLUOREN DERIVATES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | UNIV JAGIELLONSKI (PL) | 2026-04-29 | — | — | EP | disclosed |
| EP-4658639-A1 | N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-1H-IMIDAZOLE-1-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | Univerza V Ljubljani (SI) | 2025-12-10 | — | — | EP | disclosed |
| EP-0083582-A4 | IMMOBILIZED CHOLINESTERASE ENZYME PREPARATIONS AND A PROCESS FOR THE PREPARATION THEREOF. | REANAL FINOMVEGYSZERGYAR (HU) | 1984-01-31 | — | — | EP | disclosed |
| EP-0088636-A2 | Quantitative analysis apparatus and method | BIO-METRICS SYSTEMS, INC. (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0083582-A1 | IMMOBILIZED CHOLINESTERASE ENZYME PREPARATIONS AND A PROCESS FOR THE PREPARATION THEREOF. | REANAL FINOMVEGYSZERGYAR (HU) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000345-A1 | IMMOBILIZED CHOLINESTERASE ENZYME PREPARATIONS AND A PROCESS FOR THE PREPARATION THEREOF | BOROSS, László | 1983-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070286846-A1 | Novel methods for ester detoxication | CES2, BCHE, ACHE | MAPT 2176/4885SLC22A16 1216/4885CYP1A2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.