SCHEMBL77665

SCHEMBL77665

CC(=O)SC(O)C[N+](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
SLC22A16 Q86VW1 1/20 0.41
TSHR P16473 2/20 0.40
CHRM2 P08172 2/20 0.40
CHRM4 P08173 2/20 0.40
CHRM1 P11229 2/20 0.40
TBXA2R P21731 1/20 0.40
BLM P54132 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GALR3 O60755 1/20 0.39
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.37
LMNA P02545 3/20 0.34
CPT2 P23786 1/20 0.34
CPT1A P50416 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34
CYP2C9 P11712 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153646 1.00 MAPT (0.41) MAPTSLC22A16TSHRCHRM2CHRM4
Water SCHEMBL16322375 0.98 MAPT (0.40) MAPTSLC22A16TSHRCHRM2CHRM4
Bromide SCHEMBL9233901 0.98 MAPT (0.40) MAPTSLC22A16TSHRCHRM2CHRM4
Hydrochloric Acid SCHEMBL1276371 0.98 MAPT (0.45) MAPTSLC22A16TSHRCHRM2CHRM4
SCHEMBL4318608 0.98 MAPT (0.40) MAPTSLC22A16TSHRCHRM2CHRM4
Iodide SCHEMBL400576 0.98 MAPT (0.40) MAPTSLC22A16TSHRCHRM2CHRM4
Hydrochloric Acid SCHEMBL8672876 0.98 MAPT (0.45) MAPTSLC22A16TSHRCHRM2CHRM4
Bromide SCHEMBL7172545 0.98 MAPT (0.40) MAPTSLC22A16TSHRCHRM2CHRM4
Perchlorate SCHEMBL9097182 0.92 SLC22A16 (0.41) MAPTSLC22A16TSHRCHRM2CHRM4
SCHEMBL8055941 0.77 MAPT (0.39) MAPTSLC22A16TSHRCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558007-B2 In vivo enzyme activity sensors and methods ABBOTT DIABETES CARE INC. (US) 2026-02-24 US claimed
US-12559735-B2 Device for detecting organophosphates PLANTVAX, INC. (US) 2026-02-24 US claimed
US-20250222141-A1 COMPOSITION FOR THE DETECTION AND PARTIAL DECONTAMINATION OF CHEMICAL THREAT AGENTS ON SKIN SURFACE FOLLOWING DERMAL EXPOSURE THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2025-07-10 US claimed
US-20250207170-A1 CARBON CAPTURE IN TWO-STAGE FERMENTATION LANZATECH, INC. 2025-06-26 US claimed
CN-120064229-A Kanamycin sulfate identification fluorescence sensor and kanamycin sulfate detection method 河北大学 2025-05-30 CN claimed
CN-119926495-A High-entropy alloy nano enzyme, biosensor, preparation method and application thereof 重庆医科大学 2025-05-06 CN claimed
CN-119715508-A Method for detecting acetylcholinesterase based on cobalt-doped graphite-phase carbon nitride photoresponse nanoenzyme 济南大学 2025-03-28 CN claimed
EP-4525941-A1 COMPOSITION FOR THE DETECTION AND PARTIAL DECONTAMINATION OF CHEMICAL THREAT AGENTS ON SKIN SURFACE FOLLOWING DERMAL EXPOSURE The Government of The United States, as represented by The Secretary of The Army (US) 2025-03-26 EP claimed
US-20250093270-A1 Method for Detecting Enzyme Activity and Fluorescent Probe Used in Said Method THE UNIVERSITY OF TOKYO (JP) 2025-03-20 US claimed
CN-119574482-A Method for detecting chlorpyrifos by using flower-like vanadium disulfide-based biosensor and application 河南省商业科学研究所有限责任公司 2025-03-07 CN claimed
WO-2000044719-A2 1,2-DIOXETANES, PREPARATION AND USE THEREOF FOR THE DOSING OF THIOLS AND ACETYLCHOLINESTERASE COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2000-08-03 WO claimed
US-5728374-A BREAKING AND FORMING SULFIDE BONDS IN HAIR HELENE CURTIS, INC. (US) 1998-03-17 US claimed
EP-0672169-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1995-09-20 EP claimed
EP-0667141-A2 Permanent wave composition and method HELENE CURTIS, INC. (US) 1995-08-16 EP claimed
EP-0623146-A1 COMPOUNDS AND METHODS FOR INHIBITING $g(b)-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-11-09 EP claimed
US-5338663-A Interferes with formation of specific complex between alpha-antichymotrypsin and beta-protein; hydrolysis of substrate does not occur PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-08-16 US claimed
EP-0311492-B1 Kit and immunoassay method applicable to whole cells SANOFI ELF (FR) 1994-03-30 EP claimed
WO-1994005808-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1994-03-17 WO claimed
WO-1993015112-A2 COMPOUNDS AND METHODS FOR INHIBITING β-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-08-05 WO claimed
US-4273866-A IMMUNOASSAY FOR QUANTITATIVE ANALYSIS OF ACETYLCHOLINESTERASE ABBOTT LABORATORIES (US) 1981-06-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250093270-A1 Method for Detecting Enzyme Activity and Fluorescent Probe Used in Said Method ACHE, BCHE, SCLY MAPT 2473/4885SLC22A16 2348/4885TSHR 1246/4885
US-12559735-B2 Device for detecting organophosphates BCHE, LIPE, ACHE MAPT 3814/4885SLC22A16 4025/4885TSHR 4120/4885
US-12558007-B2 In vivo enzyme activity sensors and methods ACHE, CHAT, BCHE MAPT 1492/4885SLC22A16 1545/4885TSHR 2257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.