Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750464 | 0.83 | LMNA (0.45) | LMNATAAR1TRPA1MEN1KMT2A | |
| SCHEMBL608345 | 0.82 | LMNA (0.43) | LMNATAAR1TRPA1MEN1KMT2A | |
| SCHEMBL608542 | 0.79 | L3MBTL1 (0.41) | LMNAL3MBTL1TAAR1TRPA1POLB | |
| SCHEMBL10415946 | 0.79 | L3MBTL1 (0.46) | LMNAL3MBTL1TAAR1POLBHTT | |
| SCHEMBL15277287 | 0.76 | TSHR (0.39) | LMNAL3MBTL1TAAR1TRPA1POLB | |
| SCHEMBL20012560 | 0.74 | L3MBTL1 (0.44) | LMNAL3MBTL1TAAR1POLBHTT | |
| SCHEMBL11982736 | 0.74 | L3MBTL1 (0.44) | LMNAL3MBTL1TAAR1POLBHTT | |
| SCHEMBL585596 | 0.74 | L3MBTL1 (0.44) | LMNAL3MBTL1TAAR1POLBHTT | |
| SCHEMBL27389987 | 0.72 | LMNA (0.46) | LMNAL3MBTL1POLBHTTSCN1A | |
| SCHEMBL3408278 | 0.72 | LMNA (0.46) | LMNAL3MBTL1POLBHTTSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | claimed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | claimed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | claimed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | claimed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399398-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2012-02-16 | — | — | US | disclosed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071530-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080039361-A1 | Organoleptic Compounds and Their Use In Perfume Compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041077-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, TRPV1, OR51E2 | LMNA 3299/4885L3MBTL1 3149/4885TAAR1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.