Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469810 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL6086588 | 0.83 | ALDH1A1 (0.59) | ALDH1A1FEN1MAPTLMNATSHR | |
| SCHEMBL6087197 | 0.82 | ALDH1A1 (0.73) | ALDH1A1FEN1MAPTLMNATSHR | |
| SCHEMBL13041384 | 0.75 | TP53 (0.45) | ALDH1A1MAPTLMNANFKB1KMT2A | |
| SCHEMBL5531289 | 0.73 | ALDH1A1 (0.74) | ALDH1A1FEN1MAPTLMNATSHR | |
| SCHEMBL1061448 | 0.73 | L3MBTL1 (0.65) | ALDH1A1FEN1LMNAMAPK1MEN1 | |
| SCHEMBL5529505 | 0.73 | ALDH1A1 (0.81) | ALDH1A1MAPTLMNATSHRPKM | |
| SCHEMBL25111402 | 0.72 | KDM4E (0.47) | ALDH1A1MAPTLMNATSHRPKM | |
| SCHEMBL30099640 | 0.72 | KDM4E (0.47) | ALDH1A1MAPTLMNATSHRPKM | |
| SCHEMBL1996313 | 0.72 | ALDH1A1 (0.52) | ALDH1A1FEN1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019141-B2 | Quinolones with anti-HIV activity | IRM LLC (BM) | 2006-03-28 | — | — | US | disclosed |
| US-20040152719-A1 | Quinolones with anti-HIV activity | IRM LLC, A DELAWARE LLC (BM) | 2004-08-05 | — | — | US | disclosed |
| WO-2004037853-A2 | QUINOLONES WITH ANTI-HIV ACTIVITY | IRM LLC (BM) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152719-A1 | Quinolones with anti-HIV activity | NQO2, QTRT1, DHX35 | ALDH1A1 3344/4885FEN1 985/4885MAPT 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.