Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086926 | 0.89 | PDE5A (0.34) | TLR7HPGDKMT2AALDH1A1XBP1 | |
| SCHEMBL6086584 | 0.86 | DCTPP1 (0.34) | TLR7ACKR3HPGDKMT2AALDH1A1 | |
| SCHEMBL6087851 | 0.85 | GRIN1 (0.45) | TLR7TPH1TPH2 | |
| SCHEMBL6087165 | 0.84 | PDE10A (0.37) | ALDH1A1KDM4E | |
| SCHEMBL7848304 | 0.84 | TLR7 (0.33) | TLR7ACKR3KMT2AALDH1A1KDM4E | |
| SCHEMBL6086817 | 0.82 | HPGD (0.43) | TLR7HPGDKMT2AALDH1A1XBP1 | |
| SCHEMBL6087128 | 0.81 | TPH1 (0.34) | TLR7HPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL6087068 | 0.81 | DAO (0.46) | TLR7HPGDKMT2AALDH1A1NPSR1 | |
| SCHEMBL6087770 | 0.80 | TYMS (0.37) | TLR7HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL6086447 | 0.80 | MTNR1A (0.49) | HPGDKMT2AALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |