Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087128 | 0.89 | TPH1 (0.34) | TSHRHPGDGRIN1GRIN2BDAO | |
| SCHEMBL6088310 | 0.86 | GRIN1 (0.36) | GRIN1GRIN2BDAOKMT2AALDH1A1 | |
| SCHEMBL6087627 | 0.84 | TSHR (0.34) | TSHRHPGDHSD17B10GRIN1GRIN2B | |
| SCHEMBL501608 | 0.84 | GRIN1 (0.33) | TSHRHPGDHSD17B10GRIN1GRIN2B | |
| SCHEMBL6086491 | 0.84 | PDE5A (0.33) | TSHRHPGDMAPTMEN1KMT2A | |
| SCHEMBL6088314 | 0.84 | MTNR1A (0.37) | HPGDGRIN1GRIN2BDAOMAPT | |
| SCHEMBL6087770 | 0.84 | TYMS (0.37) | TSHRHPGDMAPTMEN1KMT2A | |
| SCHEMBL6087425 | 0.84 | TYMS (0.45) | TSHRHPGDHSD17B10GRIN2BDAO | |
| SCHEMBL6086817 | 0.84 | HPGD (0.43) | TSHRHPGDHSD17B10MAPTMEN1 | |
| SCHEMBL10204281 | 0.80 | TLR7 (0.35) | TSHRHPGDHSD17B10GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |