Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086577 | 1.00 | MAPT (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6085068 | 0.88 | MAPT (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6085059 | 0.88 | MAPT (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158052 | 0.78 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158053 | 0.78 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10970028 | 0.77 | MAPT (0.58) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11756343 | 0.76 | MAPT (0.60) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7540298 | 0.75 | MAPT (0.81) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158293 | 0.74 | MAPT (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1158294 | 0.74 | MAPT (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053222-B2 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S.P.A. (IT) | 2006-05-30 | — | — | US | claimed |
| EP-1495011-B1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA SPA (IT) | 2005-12-28 | — | — | EP | claimed |
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S. P. A. (IT) | 2005-03-03 | — | — | US | claimed |
| EP-1495011-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.p.A. (IT) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087077-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.P.A. (IT) | 2003-10-23 | — | — | WO | claimed |
| US-7053222-B2 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S.P.A. (IT) | 2006-05-30 | — | — | US | disclosed |
| EP-1495011-B1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA SPA (IT) | 2005-12-28 | — | — | EP | disclosed |
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S. P. A. (IT) | 2005-03-03 | — | — | US | disclosed |
| EP-1495011-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.p.A. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087077-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.P.A. (IT) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | UGT2B7, UGT2B17, CYP3A7 | MAPT 1892/4885ALDH1A1 824/4885KDM4E 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.