Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086687 | 0.86 | ROCK2 (0.36) | HDAC1HDAC8HDAC6ROCK2MEN1 | |
| SCHEMBL10204282 | 0.85 | KMT2A (0.36) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL7845897 | 0.84 | DDR1 (0.34) | ROCK2LIPEGRIN1GRIN2BPTGDR2 | |
| SCHEMBL6085657 | 0.83 | GRIN1 (0.36) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6088109 | 0.82 | KMT2A (0.37) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL6089258 | 0.81 | KMT2A (0.41) | MEN1KMT2A | |
| SCHEMBL501413 | 0.80 | KMT2A (0.35) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL12752174 | 0.79 | KMT2A (0.40) | MEN1KMT2ATDP1 | |
| SCHEMBL6634103 | 0.79 | KMT2A (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL6086806 | 0.79 | KMT2A (0.34) | HDAC8HDAC6MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |