Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336664 | 0.93 | GRIN1 (0.39) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL6087483 | 0.87 | MEN1 (0.43) | HPGDALDH1A1MAPK1KDM4EPKM | |
| SCHEMBL6087076 | 0.86 | GRIN1 (0.43) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL6089500 | 0.85 | TPH1 (0.38) | HPGDALDH1A1KDM4ELMNAPKM | |
| SCHEMBL7848789 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BHPGDALDH1A1KDM4E | |
| SCHEMBL6087879 | 0.81 | DAO (0.45) | HPGDALDH1A1KDM4EPTGDR2PKM | |
| SCHEMBL6086631 | 0.81 | GRIN1 (0.45) | GRIN1GRIN2BGABRA1GABRA5PTGDR2 | |
| SCHEMBL6086074 | 0.81 | MEN1 (0.35) | HPGDALDH1A1POLBKDM4ELMNA | |
| SCHEMBL6089230 | 0.81 | TYMS (0.38) | HPGDALDH1A1MAPK1LMNA | |
| SCHEMBL6086116 | 0.81 | GRIN1 (0.37) | GRIN1GRIN2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |