Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637345 | 0.89 | GAA (0.39) | HPGDPOLBTLR7PKMKDM4E | |
| SCHEMBL6089258 | 0.87 | KMT2A (0.41) | HPGDALDH1A1POLBTLR7PKM | |
| SCHEMBL6088109 | 0.86 | KMT2A (0.37) | HPGDALDH1A1POLBPKMKDM4E | |
| SCHEMBL6087630 | 0.86 | GRIN1 (0.44) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL6640101 | 0.84 | GRIN1 (0.33) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL7837543 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BPOLBTLR7PKM | |
| SCHEMBL6634103 | 0.83 | KMT2A (0.38) | HPGDALDH1A1POLBTLR7KDM4E | |
| SCHEMBL6086464 | 0.83 | DAO (0.44) | HPGDALDH1A1TLR7PKMKDM4E | |
| SCHEMBL10204262 | 0.82 | KMT2A (0.35) | GRIN1GRIN2BPOLBTLR7GABRA1 | |
| SCHEMBL6636863 | 0.82 | GRIN1 (0.44) | GRIN1GRIN2BALDH1A1POLBTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |