Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449593 | 0.87 | CCR5 (0.43) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL17141012 | 0.85 | DDB1 (0.46) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL6087981 | 0.80 | USP2 (0.40) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL29788253 | 0.79 | USP2 (0.44) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL4137608 | 0.79 | USP2 (0.39) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL8893424 | 0.74 | CCR5 (0.51) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL17149526 | 0.74 | CCR5 (0.53) | CCR5USP2KDM4ENPC1L1ALOX15 | |
| SCHEMBL31283197 | 0.74 | DDB1 (0.45) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL27152573 | 0.74 | CCR5 (0.53) | DDB1CRBNCCR5USP2SMN1; SMN2 | |
| SCHEMBL660313 | 0.74 | GPR119 (0.52) | DDB1CRBNCCR5SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115601-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-03 | — | — | US | disclosed |
| US-20050261322-A1 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261322-A1 | HIV integrase inhibitors | TYMP, PAICS, TYMS | DDB1 776/4885CRBN 4140/4885CCR5 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.