Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Benzotriazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.37 |
| ▸ | BTK known ✓ | Q06187 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzotriazole SCHEMBL27438561 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL9059391 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL28261313 | 0.98 | ALDH1A1 (0.38) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL28091111 | 0.98 | ALDH1A1 (0.38) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL8956 | 0.97 | — | — | |
| Benzotriazole SCHEMBL6088869 | 0.97 | ALDH1A1 (0.41) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL29381270 | 0.97 | — | — | |
| Benzotriazole SCHEMBL4459859 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL3665910 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9APKM | |
| Benzotriazole SCHEMBL3018142 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907279-A | Synthesis method of N-oxyphenyltriazole | 金华职业技术学院 | 2022-08-16 | — | — | CN | claimed |
| CN-109252165-A | A kind of preparation method for subtracting copper liquid subtracting copper composition and include the composition | 苏州纳勒电子科技有限公司 | 2019-01-22 | — | — | CN | claimed |
| CN-108795129-A | A kind of preparation method of polyacrylate/benzotriazole@zinc oxide microcapsules composite anti-corrosive coatings | 陕西科技大学 | 2018-11-13 | — | — | CN | claimed |
| CN-108623019-A | A kind of sea water desalination antisludging agent and preparation method thereof | 苏州佑君环境科技有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-105432625-B | Polybenzobisoxazole zinc and sterol demethylation inhibitor class（DMIs）The composition and its preparation of fungicide and application | 浙江新农化工股份有限公司 | 2018-07-27 | — | — | CN | claimed |
| CN-104981160-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-04-20 | — | — | CN | claimed |
| CN-104981154-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-01-26 | — | — | CN | claimed |
| CN-104378986-B | Pesticidal compositions and methods related thereto | 陶氏益农公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106458860-A | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106234467-A | A kind of antibacterial and preparation method thereof | 吴远宁 | 2016-12-21 | — | — | CN | claimed |
| CN-106061254-A | Use of pesticidal active carboxamide derivative in soil and seed application and treatment methods | 巴斯夫农业化学品有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105899073-A | Insecticidal active mixtures comprising carboxamide compound | 巴斯夫农业化学品有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-100526269-C | Bis (2-acenyl) acetylene semiconductors | 3M INNOVATIVE PROPERTIES CO (US) | 2009-08-12 | — | — | CN | claimed |
| CN-1823027-A | Bis(2-acenyl)acetylene semiconductors | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-23 | — | — | CN | claimed |
| US-6783743-B1 | COMPONENTS AND PRODUCT LOSS ARE SUBSTANTIALLY ELIMINATED BY RECOVERING MATERIALS FROM VARIOUS UNITS OF THE APPARATUS, AND RECYCLING THE MATERIALS BACK TO THE RESPECTIVE UNITS | PURITAN PRODUCTS, INC. | 2004-08-31 | — | — | US | claimed |
| CN-1252069-A | 5,6, 7-trisubstituted-4-aminopyrido [2, 3-d ] pyrimidine compounds | ABBOTT LAB (US) | 2000-05-03 | — | — | CN | claimed |
| US-4359397-A | WATER RELEASING WHEN MELTED | POLAROID CORPORATION (US) | 1982-11-16 | — | — | US | claimed |
| CN-118843626-A | Heterocyclic compounds as DYRK1A inhibitors | 普罗塞纳生物科学有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-0076758-A2 | 4-Ether derivatives of 2-azetidinone-1-sulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4359397-A | WATER RELEASING WHEN MELTED | POLAROID CORPORATION (US) | 1982-11-16 | — | — | US | disclosed |