Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088875 | 0.89 | MAOB (0.53) | MAOBMRGPRX4 | |
| SCHEMBL6088282 | 0.86 | ALOX5 (0.42) | MRGPRX4 | |
| SCHEMBL6091382 | 0.85 | CCNB2 (0.40) | MAOBSMN1; SMN2NR4A2 | |
| SCHEMBL6090892 | 0.84 | BCHE (0.40) | FFAR1MAOBNR4A2 | |
| SCHEMBL6089755 | 0.84 | TSHR (0.45) | FFAR1MAOBMRGPRX4SMN1; SMN2NR4A2 | |
| SCHEMBL6088358 | 0.84 | BCHE (0.38) | FFAR1MAOBMRGPRX4NR4A2 | |
| SCHEMBL6088820 | 0.82 | FFAR1 (0.55) | FFAR1FFAR4MRGPRX4LTA4HPLA2G2A | |
| SCHEMBL6089979 | 0.82 | MRGPRX4 (0.41) | FFAR1MAOBMRGPRX4NR4A2 | |
| SCHEMBL6088303 | 0.82 | NOS3 (0.46) | MAOBSMN1; SMN2 | |
| SCHEMBL27484684 | 0.82 | SLC22A12 (0.40) | FFAR1MAOBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |