Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091382 | 0.90 | CCNB2 (0.40) | MAOBNR4A2 | |
| SCHEMBL6098220 | 0.89 | BCHE (0.42) | BCHEMAOBMAOAFFAR1MTNR1A | |
| SCHEMBL6089097 | 0.84 | FFAR1 (0.45) | MAOBFFAR1NR4A2 | |
| SCHEMBL6090183 | 0.82 | PTGER1 (0.50) | PTGER4PTGER3PTGER2PTGER1FFAR1 | |
| SCHEMBL6088282 | 0.82 | ALOX5 (0.42) | — | |
| SCHEMBL6088875 | 0.82 | MAOB (0.53) | MAOB | |
| SCHEMBL27484684 | 0.82 | SLC22A12 (0.40) | BCHEPTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL5725263 | 0.82 | SCN8A (0.38) | FFAR1 | |
| SCHEMBL6088358 | 0.81 | BCHE (0.38) | BCHEMAOBFFAR1NR4A2 | |
| SCHEMBL6089755 | 0.81 | TSHR (0.45) | MAOBFFAR1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |