SCHEMBL6089113

SCHEMBL6089113

COC(=O)c1ccc2onc(N)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
HSD17B10 Q99714 4/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
ATM Q13315 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
XDH P47989 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
HIF1A Q16665 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.44
TP53 P04637 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6089216 0.88 MAPT (0.51) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL29652456 0.88 MAPT (0.51) MAPTKDM4EALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL6089209 0.87 MAPT (0.50) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6778897 0.83 CA12 (0.53) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL30040356 0.83 CA12 (0.49) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL15660075 0.83 CA12 (0.49) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL5618133 0.78 HIF1A (0.42) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL21596905 0.78 MAPK14 (0.44) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL23535844 0.77 HTR1F (0.50) CA12CA1CA2CA7XDH
SCHEMBL25353360 0.77 NPC1 (0.56) ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed
US-20060235222-A1 Indole-derivative modulators of steroid hormone nuclear receptors ELI LILLY AND COMPANY (US) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS MAPT 2060/4885KDM4E 2188/4885ALDH1A1 2774/4885
US-20060235222-A1 Indole-derivative modulators of steroid hormone nuclear receptors NR3C2, NR5A1, MC2R MAPT 4025/4885KDM4E 3154/4885ALDH1A1 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.