Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959935 | 0.83 | SLC2A1 (0.49) | POLBNPSR1HDAC1HDAC6GPR39 | |
| SCHEMBL2041332 | 0.81 | NPSR1 (0.68) | ALDH1A1TP53HSD17B10NPSR1MEN1 | |
| SCHEMBL2599927 | 0.81 | POLB (0.50) | POLBALDH1A1MAP4K4TP53HSD17B10 | |
| SCHEMBL7531482 | 0.78 | NPSR1 (0.46) | ALDH1A1HSD17B10NPSR1MEN1LMNA | |
| SCHEMBL1267632 | 0.77 | ALDH1A1 (0.50) | POLBALDH1A1MAP4K4TP53HSD17B10 | |
| SCHEMBL31240581 | 0.76 | FABP1 (0.55) | POLBALDH1A1MAP4K4MEN1LMNA | |
| SCHEMBL1666510 | 0.75 | KDM4E (0.57) | POLBALDH1A1MAP4K4GPR39MEN1 | |
| SCHEMBL29579775 | 0.75 | ALDH1A1 (0.65) | POLBALDH1A1MAP4K4HSD17B10NPSR1 | |
| SCHEMBL34462729 | 0.74 | MAP4K4 (0.52) | POLBALDH1A1MAP4K4TP53HSD17B10 | |
| SCHEMBL2599917 | 0.73 | PKM (0.68) | POLBALDH1A1MAP4K4HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006021848-A1 | ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-03-02 | — | — | WO | disclosed |