Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GPR39 | O43194 | 1/20 | 0.47 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089226 | 0.83 | POLB (0.50) | NPSR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL1666510 | 0.78 | KDM4E (0.57) | MEN1KMT2AHPGDLMNAPOLB | |
| SCHEMBL29580189 | 0.76 | POLB (0.69) | SLC2A1NPSR1MEN1KMT2AHPGD | |
| SCHEMBL960125 | 0.72 | PTGDR (0.57) | NPSR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL11512272 | 0.71 | MAPT (0.56) | NPSR1MEN1KMT2ALMNAGAA | |
| SCHEMBL2041332 | 0.71 | NPSR1 (0.68) | NPSR1MEN1KMT2AHPGDLMNA | |
| SCHEMBL26971122 | 0.71 | CCR4 (0.46) | MEN1KMT2ALMNACCR4PKM | |
| SCHEMBL31478745 | 0.69 | MAPT (0.60) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL31240581 | 0.69 | FABP1 (0.55) | MEN1KMT2AHPGDLMNAPOLB | |
| SCHEMBL7531482 | 0.69 | NPSR1 (0.46) | NPSR1MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | SLC2A1 1702/4885NPSR1 122/4885MEN1 4161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.