Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089419 | 0.84 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2MAPTHTTSMN1; SMN2 | |
| SCHEMBL6092367 | 0.77 | LMNA (0.48) | CYSLTR1CYSLTR2PPARDPPARALMNA | |
| SCHEMBL6090709 | 0.75 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL6088572 | 0.72 | MAPT (0.44) | CYSLTR1MAPTHTTSMN1; SMN2ALOX5 | |
| SCHEMBL6088343 | 0.72 | MAPT (0.41) | CYSLTR1MAOBMAPTHTTSMN1; SMN2 | |
| SCHEMBL6088023 | 0.70 | MAPT (0.46) | CYSLTR1CYSLTR2MAOBMAPTHTT | |
| SCHEMBL6089262 | 0.68 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL6088658 | 0.67 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2ALOX5PPARG | |
| SCHEMBL6090373 | 0.67 | MRGPRX4 (0.59) | MAOBSMN1; SMN2PPARDFFAR1PPARA | |
| SCHEMBL10546719 | 0.67 | CYSLTR1 (0.72) | CYSLTR1SMN1; SMN2KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |